--- product_id: 715574302 title: "Zymox Advanced Formula Otic Plus Enzymatic Ear Solution for Dogs and Cats with 1% Hydrocortisone, 1.25oz" brand: "zymox" price: "£50.96" currency: GBP in_stock: true reviews_count: 5 category: "Zymox" url: https://www.desertcart.co.uk/products/715574302-zymox-advanced-formula-otic-plus-enzymatic-ear-solution-for-dogs store_origin: GB region: United Kingdom --- # 1.25oz easy-apply clear solution LP3 Enzyme System for deep biofilm penetration 1% Hydrocortisone soothes itching & redness Zymox Advanced Formula Otic Plus Enzymatic Ear Solution for Dogs and Cats with 1% Hydrocortisone, 1.25oz **Brand:** zymox **Price:** £50.96 **Availability:** ✅ In Stock ## Summary > 🐾 Clear ears, happy pets — because your furry friend deserves the best! ## Quick Answers - **What is this?** Zymox Advanced Formula Otic Plus Enzymatic Ear Solution for Dogs and Cats with 1% Hydrocortisone, 1.25oz by zymox - **How much does it cost?** £50.96 with free shipping - **Is it available?** Yes, in stock and ready to ship - **Where can I buy it?** [www.desertcart.co.uk](https://www.desertcart.co.uk/products/715574302-zymox-advanced-formula-otic-plus-enzymatic-ear-solution-for-dogs) ## Best For - zymox enthusiasts ## Why This Product - Trusted zymox brand quality - Free international shipping included - Worldwide delivery with tracking - 15-day hassle-free returns ## Key Features - • **Itch-Relief Power:** 1% Hydrocortisone calms irritation and redness fast, no harsh pre-cleaning needed - • **Safe for All Ages:** Gentle, natural alternative suitable for dogs and cats of every life stage - • **Vet-Trusted Since 1998:** Clinically proven formula trusted by professionals for over two decades - • **Biofilm-Busting Enzymes:** Patented LP3 Enzyme System penetrates stubborn ear biofilms for deep cleaning - • **Cruelty-Free & Made in USA:** Ethically produced with no animal testing, supporting conscious pet care ## Overview Zymox Advanced Formula Otic Plus is a veterinarian-recommended enzymatic ear solution for dogs and cats, featuring a patented LP3 Enzyme System that penetrates and breaks down biofilms caused by bacteria, fungi, and yeast. Enhanced with 1% Hydrocortisone, it soothes itching and redness without the need for painful pre-cleaning. Suitable for pets of all ages, this 1.25oz cruelty-free formula is proudly made in the USA and offers a natural, effective alternative to traditional medications. ## Description Trusted by Veterinarians since 1998. ZYMOX Ear Solution with hydrocortisone aids in managing problematic ears on all animals including dogs and cats of any age. The patented LP3 Enzyme System delivers a potent formula to maximize the power of this product, without traumatic pre-cleaning and application. Otic Plus system works to penetrate deeper into the underlying bacteria's protective biofilm.1% Hydrocortisone is added for comfort. Use once daily for 7 to 14 days. For maintaining clean and healthy ears after the course of Ear Solution, use ZYMOX Ear Cleanser weekly. This product is proudly made in the USA. Animal Cruelty-Free and is never tested on animals. Item dimensions; 1.88"L x 1.13"W x 3.88"H, 1.25 Fluid Ounces (37ml). Review: I bought Zymox Plus for my dog after I had a strong irritation in my ears caused by a talc I used previously to clean and remove hairs from the ear canal. That product caused a pretty strong reaction, with inflammation, redness and secretion, which worried me a lot. I decided to try Zymox Plus and, from the first use, I noticed an improvement. The inflammation has been going down, the redness has decreased and my dog looks much more comfortable and calm. I have also noticed less discomfort and improvement in ear cleaning. In my personal experience, it has been a very useful product to help in the recovery and relief of the discomfort of my pet. I recommend it for similar cases, always observing the evolution of the animal and consulting the veterinarian if necessary. Review: Wow! My dog had what I interpreted as excessive wax build up in his ear. He’s a feisty little guy and I could not get on top of it with mere cleaning and hair trimming. With a yeasty smell I turned to this product. The debris that came out of his ear was phenomenal, and now he is irritation free with a very clean ear canal. This product is highly recommended. ## Features - Cat and dog ear cleaner, soothes recurrent ear issues, itching and redness, for pets of all ages - Relief from stubborn ear problem-causing microorganisms that form complex, irritating biofilms - Gentle formula helps relieve painful ear issues caused by resistant germs, fungi and yeast - Pet ear solution, no pre-cleaning of painful ears needed; safe, natural alternative to medication - LP3 Enzyme System to help clear ear exudate; 1% Hydrocortisone for itchy ears ## Technical Specifications | Specification | Value | |---------------|-------| | ASIN | B0066VLPGA | | Allergen Information | Abalone Free | | Batteries Included | No | | Best Sellers Rank | #3,629 in Pet Supplies ( See Top 100 in Pet Supplies ) #12 in Dog Ear Care #77 in Cat Health Supplies | | Color | Original Version | | Customer Reviews | 4.7 4.7 out of 5 stars (13,255) | | Date First Available | 16 October 2013 | | Item Weight | 36.8 g | | Item model number | 441125 | | Number of Items | 1 | | Pet Life Stage | All Life Stages | | Pet Type | Cat, Dog, Kitten, Pet, Puppy | | Product Dimensions | 19.69 x 10.8 x 9.53 cm; 36.85 g | | Quantity | 1 | | Size | 55 g | | Specific Uses | EAR | | batteries required | No | ## Images ![Zymox Advanced Formula Otic Plus Enzymatic Ear Solution for Dogs and Cats with 1% Hydrocortisone, 1.25oz - Image 1](https://m.media-amazon.com/images/I/512WnsXPqIL.jpg) ![Zymox Advanced Formula Otic Plus Enzymatic Ear Solution for Dogs and Cats with 1% Hydrocortisone, 1.25oz - Image 2](https://m.media-amazon.com/images/I/81bWD55aVhL.jpg) ![Zymox Advanced Formula Otic Plus Enzymatic Ear Solution for Dogs and Cats with 1% Hydrocortisone, 1.25oz - Image 3](https://m.media-amazon.com/images/I/71qTJTpVMzL.jpg) ![Zymox Advanced Formula Otic Plus Enzymatic Ear Solution for Dogs and Cats with 1% Hydrocortisone, 1.25oz - Image 4](https://m.media-amazon.com/images/I/717Im5bW39L.jpg) ![Zymox Advanced Formula Otic Plus Enzymatic Ear Solution for Dogs and Cats with 1% Hydrocortisone, 1.25oz - Image 5](https://m.media-amazon.com/images/I/81u5NQFW9jL.jpg) ## Questions & Answers **Q: How is Zymox Plus different from Zymox (with the blue label)? both say 1.0 hydrocortisone.** A: My veterinarian said just to use the regular Zymox. It’s $10 cheaper and has the exact same ingredient. I looked it up myself. You can see the active ingredient in the inactive ingredient. Everything is the same. It’s kind of like the namebrand Excedrin. They they packaged their product in different ways. They have Excedrin for headaches Excedrin for migraine. Exactly the same product. A lot of companies do that apparently. Hope this helps **Q: how do you get all the wax off the inside of the ears where it flushes out from the ear drops** A: This is a bit thicker, kind of like the consistency of neosporin, so if your dogs ears are really wax-y right now, I would suggest doing a light cleaning before putting this in the ears. Once you put the zymox into the ear, rub your dogs ears kind of in a circular motion to help massage the solution down into the ear canal, and then just let it sit and do it's thing. Over time there will be less wax build up to clean out before applying the ointment. I now put it in my dogs ears about once every 10 to 15 days, just as maintenance and care, without needing any wax clean up before hand or afterwards. **Q: Is this supposed to be liquidy/thin like water (not thick)? What I received is a different consistency than the thicker regular zymox I'm used to.** A: I ordered and received a bottle this week and the solution is much thinner than the previous zymox plus otic-hc advanced formula bottles I've ordered. I haven't used it yet but just by shaking the bottle I can tell it is very liquidy compared to the bottle I have left over. I also compared the boxes and the box I received this week looks different as well. The font is different and the box has a different texture. I also read the paper inside and noticed a major typo on the one I just received. Instead of spelling "externa" they spelled "exernna" 🤦🏽‍♀️ The boxes have different lot numbers and the box that I have already opened has a later expiration date than the box I just received. I hope they didn't send me a knock off. This enzymatic solution usually works wonders on my Boxer and completely cures her ear infections when I use it as directed. I will update you on the effectiveness of the bottle I just received after I use it. **Q: is this the same as Mometamax 15g** A: No Different item Mometamax is stronger and is prescription medication. ## Customer Reviews ### ⭐⭐⭐⭐⭐ Review *by E***A on 18 April 2026* I bought Zymox Plus for my dog after I had a strong irritation in my ears caused by a talc I used previously to clean and remove hairs from the ear canal. That product caused a pretty strong reaction, with inflammation, redness and secretion, which worried me a lot. I decided to try Zymox Plus and, from the first use, I noticed an improvement. The inflammation has been going down, the redness has decreased and my dog looks much more comfortable and calm. I have also noticed less discomfort and improvement in ear cleaning. In my personal experience, it has been a very useful product to help in the recovery and relief of the discomfort of my pet. I recommend it for similar cases, always observing the evolution of the animal and consulting the veterinarian if necessary. ### ⭐⭐⭐⭐⭐ Review *by J***S on 22 February 2026* Wow! My dog had what I interpreted as excessive wax build up in his ear. He’s a feisty little guy and I could not get on top of it with mere cleaning and hair trimming. With a yeasty smell I turned to this product. The debris that came out of his ear was phenomenal, and now he is irritation free with a very clean ear canal. This product is highly recommended. ### ⭐⭐⭐⭐⭐ Review *by R***L on 22 March 2026* This stuff worked wonders for my dog’s ears. I saw a review about it turning a dog’s ears red. So I read the instructions very carefully & it clearly states on the bottle if your dog is allergic to the ingredients not to use it. I was unsure if my dog was or not, so i decided to buy it & do a patch test first. Because she was excessively digging at her ears & scratching them. So when I receive the product, I did examine her ears quite well to make sure she had no open sores in them. Since she didn’t have any open sources on them . I Then did a patch test on the inside tip of her ear & waited 24 hours, to make sure she was not allergic to it. Then I proceeded as the instructions said within the first three days her ears cleared up. And they were no longer black inside & she stopped itching. It saved me a trip to the vet that’s for sure. Highly recommend this. This product hasNo smell that i noticed. It is pretty thick & clear looking so it makes it easy to apply how much you’re putting on the dog ear. ## Frequently Bought Together - Zymox Advanced Formula Otic Plus Enzymatic Ear Solution for Dogs and Cats with 1% Hydrocortisone, 1.25oz - Zymox Advanced Enzymatic Ear Wipes for Dogs and Cats - for Dirty, Waxy, Smelly Ears - Premium Strength Ear Cleaner Wipes - Non-Irritating - Hypoallergenic - 100 ct - Zymox Ear Cleanser Solution for Dogs and Cats, 4oz --- ## Why Shop on Desertcart? - 🛒 **Trusted by 1.3+ Million Shoppers** — Serving international shoppers since 2016 - 🌍 **Shop Globally** — Access 737+ million products across 21 categories - 💰 **No Hidden Fees** — All customs, duties, and taxes included in the price - 🔄 **15-Day Free Returns** — Hassle-free returns (30 days for PRO members) - 🔒 **Secure Payments** — Trusted payment options with buyer protection - ⭐ **TrustPilot Rated 4.5/5** — Based on 8,000+ happy customer reviews **Shop now:** [https://www.desertcart.co.uk/products/715574302-zymox-advanced-formula-otic-plus-enzymatic-ear-solution-for-dogs](https://www.desertcart.co.uk/products/715574302-zymox-advanced-formula-otic-plus-enzymatic-ear-solution-for-dogs) --- *Product available on Desertcart United Kingdom* *Store origin: GB* *Last updated: 2026-05-16*