Advantage II Medium Dog

​Finding an effective flea treatment for a large dog can be a challenge, but Advantage II has always been my go-to. This 4-month supply for dogs 55+ lbs is perfect for keeping my dog protected throughout the season. It’s easy to apply, waterproof, and I love that it kills fleas at all life stages—larvae and eggs included—so we don't have to deal with any re-infestations. My order was delivered right on time on May 8th, and it's such a relief to have peace of mind knowing he's covered. Highly recommend for any large breed owners!

This stuff works like magic a very well flea killer she is one happy dog!

Excellent product

This stuff used to work great but seems like now it doesn't work as good but still knocks them down a bit

We have double coated, long haired, very furry large Northern Breed Mixed Dogs. Unfortunately, fleas are a year round problem here in the San Francisco Bay Area where we live ... Ugh! Advantage II Topical Flea Treatment & Prevention is an effective tool in our flea control regimen. - Easy to apply the topical drops on your dog's skin along the backbone. - Our dogs have never had any skin irritation or other negative reactions with this product. - The 6 pack is a terrific value. I highly recommend this product.

I've been using Advantage for flea control for several years, and Amazon is one of the best places to get it. You can't beat $10 a month for large dog flea protection. I also use one tube split into fifths (via syringe measurement) to give to my cats. Advantage II specifically is exactly the same product, in different dosages, for both dogs and cats. My 70-lb Lab gets a full 40 ml tube by herself, then the cats get 8 ml each and my brother-in-law's two ferrets get 4 ml each. I can cover 7 pets for $20 a month- a fantastic deal. The Advantage makes a noticeable difference in my pets' comfort- towards the end of the month, when it's wearing off, they begin to get itchy and uncomfortable. Once I reapply, that stops within a day or two, and they're happy and flea-free again all month. I have noticed that if our dog regularly gets into water (pool, beach, sprinklers), the Advantage wears off much quicker, despite claiming to be waterproof. That's understandable in a topical treatment, so we try to keep her out of water until the end of the application cycle, before a new treatment- then she gets to get wet to her heart's content! If you need to bathe your dog to kill fleas before applying, be sure to wait a day or two after the bath to give your dog's natural skin oils a chance to bounce back- it helps to distribute the medication. Be aware: this product is alcohol-based, and will evaporate quickly if left out in open air (we use a glass baby food jar to split the dosages in the syringe). It has also stripped the lacquer off the dining table when a few drops spilled while splitting doses, so try to avoid that too! Other than that, Advantage II is, in my opinion, the best topical flea control.

So far I haven't noticed any fleas. But it may not be time for them yet.

Works well but my dog smells absolutely awful for a few days after application. I don’t know if he has a reaction to it or what but the smell is enough to make me change to something else.