--- product_id: 4115189 title: "Seriphos - Phosphorylated Serine Adaptogen - Cortisol Supplement - Helps Cognitive Function, Gluten Free, Dairy Free, Soy Free - 100 Capsules" brand: "interplexus" price: "£39.67" currency: GBP in_stock: true reviews_count: 8 category: "Inter Plexus" url: https://www.desertcart.co.uk/products/4115189-seriphos-phosphorylated-serine-adaptogen-cortisol-supplement-helps-cognitive-function-gluten store_origin: GB region: United Kingdom --- # Gluten, dairy, soy free clean formula 100 capsules for sustained brain support Phosphorylated serine to balance cortisol levels Seriphos - Phosphorylated Serine Adaptogen - Cortisol Supplement - Helps Cognitive Function, Gluten Free, Dairy Free, Soy Free - 100 Capsules **Brand:** interplexus **Price:** £39.67 **Availability:** ✅ In Stock ## Summary > 🧬 Unlock your brain’s calm and clarity with Seriphos — stress less, live more! ## Quick Answers - **What is this?** Seriphos - Phosphorylated Serine Adaptogen - Cortisol Supplement - Helps Cognitive Function, Gluten Free, Dairy Free, Soy Free - 100 Capsules by interplexus - **How much does it cost?** £39.67 with free shipping - **Is it available?** Yes, in stock and ready to ship - **Where can I buy it?** [www.desertcart.co.uk](https://www.desertcart.co.uk/products/4115189-seriphos-phosphorylated-serine-adaptogen-cortisol-supplement-helps-cognitive-function-gluten) ## Best For - interplexus enthusiasts ## Why This Product - Trusted interplexus brand quality - Free international shipping included - Worldwide delivery with tracking - 15-day hassle-free returns ## Key Features - • **Nighttime Reset Ritual:** Trusted by users to normalize cortisol peaks and improve sleep quality without dependency. - • **Cognitive Clarity Boost:** Ethanolamine enhances cellular communication for sharper focus and mental agility. - • **Clean & Conscious Formula:** Free from gluten, dairy, soy, and GMOs—perfect for mindful wellness seekers. - • **Stress Mastery in a Capsule:** Clinically designed phosphorylated serine supports healthy cortisol rhythms to keep you calm under pressure. - • **100 Capsules of Adaptogenic Power:** A full supply to help you build resilience and maintain a balanced mood daily. ## Overview Seriphos by InterPlexus is a premium phosphorylated serine supplement formulated to support healthy cortisol levels and cognitive function. With 100 vegetarian capsules free from gluten, dairy, soy, and GMOs, it promotes stress resilience, balanced mood, and improved sleep quality, making it an essential adaptogen for adults managing chronic stress. ## Description Phosphorylated Serine/Ethanolamine Other Ingredients: Cellulose, vegetarian capsule shell (hypromellose, water)Seriphos for Adaptogen and Adrenal Support by InterPlexus, 100 capsu Review: Helps so much - I've used this supplement for many years. When I was having issues with my adrenal gland, my doctor recommended I start taking this every night. My cortisol had been peaking at noon instead of a 8am and this is the ONLY thing that helped me get back to sleeping more normal and waking up at a normal time in the morning. These have no aftertaste, are decently sized but not too hard to swallow (in my opinion) and the shipping is always quick. The value is great considering it actually helps. It took me a few months of taking this to get lasting results but I still take some every night and it really does help keep my cortisol levels balanced. Review: Works as advertised. Original Formula. (long). - 65 years old, good health, man, I have had the typical middle-insomnia problem for about 10 years. I oscillated between resigning to it as an "old man thing" and trying to fight it off with different types of products, OTC sleep-aids, melatonin but stayed off Rx because of the cycle of dependence I have seen developing in people who used it regularly. I stayed off of psychotropics such as Trazodone as well for the same reasons. I struggled to understand whether this was depression or anxiety and finally settled for high/dysfunctional cortisol levels due to chronic stress (e.g. parents getting old and dependent, buying a large house, other life issues). Since I can't change my life to remove the stress, I looked around for cortisol agonists and found Seriphos. I noticed a change starting the first night with one capsule. The effect was not magical (i.e. full night of restful sleep) but did make a difference in that my awakenings were shorter and the depressive thoughts that invariably came with it (i.e. "negative auto-brooding") took a superficial tone and evaporated rapidly. I also noticed that my dreams, for the first couple of weeks at least, were less intense but much longer and wide-ranging. This was very surprising to me: it felt like I was catching up with dream-work somehow . I am now over 1 month into it and the 2/3 am awakening has become very variable and very brief. I wake up fully rested even if some nights, I have the feeling of not sleeping very smoothly. Gradually, I came to trust the effect, which probably reinforces it. Zero side-effects for me. Depending on one's metabolism, there will be some trial and error as to when to take it. I take it at around 9. The catch is to have the effect kick in at or just before the usual awakening time. This product does work and there is a simple, clear and logical explanation of why it does so that the placebo effect cannot account entirely for its efficacy. I reached the point where I am planning how to discontinue. I decided for 6 weeks of use. The hope, of course, is that the effect will continue, although, since the cortisol hypothesis has been confirmed in my case, chronic stress will likely take over eventually (until I change my life!). It will be interesting to see how long it takes and if there are any other changes. ## Features - MAINTAINS A HEALTHY STRESS RESPONSE - Seriphos contains key nutrients that help maintain healthy cortisol (the stress hormone) levels. * - SUPPORTS HEALTHY CORTISOL LEVELS - Seriphos is formulated using phosphorylated serine which can improve your adaptability to unhealthy stress, support a normal mood, and encourage healthy cognitive function. * - ENCOURAGES HEALTHY COGNITIVE FUNCTION - The ethanolamine contained in Seriphos serve as biological building blocks used by the cell to increase cellular health and promote cellular transmission maintaining healthy cognitive function.* - PROMOTES A HEALTHY MOOD - The Phosphatidylserine produces by the body as a result of Seriphos supplementation may help maintain a healthy mood.* - *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. ## Technical Specifications | Specification | Value | |---------------|-------| | ASIN | B00747NHTI | | Age Range Description | Adult | | Allergen Information | Beef Free, Corn-Free, Dairy Free, Egg Free, Fish Free, Gluten Free, Shellfish Free, Soy Free, Wheat Free | | Best Sellers Rank | #38,860 in Health & Household ( See Top 100 in Health & Household ) #1,361 in Blended Vitamin & Mineral Supplements | | Brand | InterPlexus | | Brand Name | InterPlexus | | Container Type | Bottle | | Customer Reviews | 4.4 out of 5 stars 853 Reviews | | Diet Type | Gluten Free, Vegetarian | | Dosage Form | Capsule | | Flavor | Unflavored | | Item Form | Capsule | | Item Weight | 0.3 Pounds | | Manufacturer | InterPlexus | | Manufacturer Part Number | PHOSSx2 | | Material Features | GMO Free | | Material Type Free | Corn Free, Egg Free, Soy Free, Yeast Free, wheat Free | | Number of Items | 1 | | Pill Coating | Uncoated | | Primary Supplement Type | Phyosphorylated Serine | | Product Benefits | Brain Health Support | | Total Servings Per Container | 100 | | UPC | 702383482908 | | Unit Count | 100.0 Count | ## Product Details - **Age Range (Description):** Adult - **Brand:** InterPlexus - **Diet Type:** Gluten Free, Vegetarian - **Flavor:** Unflavored - **Item Form:** Capsule - **Item Weight:** 4.8 ounces - **Package Information:** Bottle - **Primary Supplement Type:** Phyosphorylated Serine - **Product Benefits:** Brain Health Support - **Unit Count:** 100.0 Count ## Images ![Seriphos - Phosphorylated Serine Adaptogen - Cortisol Supplement - Helps Cognitive Function, Gluten Free, Dairy Free, Soy Free - 100 Capsules - Image 1](https://m.media-amazon.com/images/I/41Mn8KVaWzL.jpg) ## Questions & Answers **Q: Does this product contain soy?** A: No is does not contain soy. **Q: Has anyone bought this after December 2016 that can post the ingredients? They are supposed to bring the original formula back now.** A: The new (old) Seriphos is out and selling: Seriphos®Supports a healthy and balanced stress response*ORIGINAL FORMULAwith Phosphorylated Serine.Seriphos is an adaptogen and adrenal support formula that contains key nutrients for stress resiliency including phosphoserine, magnesium, calcium and phosphorus. This formula assists in balancing cortisol when levels are elevated due to acute or chronic stress.* 100 Capsules **Q: Is this the new old formula or the old new formula? I want the one with the 1000 mg of the product that worked.** A: Currently the Seriphos being sold is the new formula. However, I got an email from InterPlexus on Dec. 19th (2016) that said management had decided to go back to the old formula due to high customer demand. The old formula was suppose to be available again by the end of 2016. Hope this helps! **Q: How many capsules make 1000mg?** A: The product description says the serving size of 1 capsule contains 1000 mg. ## Customer Reviews ### ⭐⭐⭐⭐⭐ Helps so much *by R***W on January 6, 2026* I've used this supplement for many years. When I was having issues with my adrenal gland, my doctor recommended I start taking this every night. My cortisol had been peaking at noon instead of a 8am and this is the ONLY thing that helped me get back to sleeping more normal and waking up at a normal time in the morning. These have no aftertaste, are decently sized but not too hard to swallow (in my opinion) and the shipping is always quick. The value is great considering it actually helps. It took me a few months of taking this to get lasting results but I still take some every night and it really does help keep my cortisol levels balanced. ### ⭐⭐⭐⭐⭐ Works as advertised. Original Formula. (long). *by F***K on March 27, 2017* 65 years old, good health, man, I have had the typical middle-insomnia problem for about 10 years. I oscillated between resigning to it as an "old man thing" and trying to fight it off with different types of products, OTC sleep-aids, melatonin but stayed off Rx because of the cycle of dependence I have seen developing in people who used it regularly. I stayed off of psychotropics such as Trazodone as well for the same reasons. I struggled to understand whether this was depression or anxiety and finally settled for high/dysfunctional cortisol levels due to chronic stress (e.g. parents getting old and dependent, buying a large house, other life issues). Since I can't change my life to remove the stress, I looked around for cortisol agonists and found Seriphos. I noticed a change starting the first night with one capsule. The effect was not magical (i.e. full night of restful sleep) but did make a difference in that my awakenings were shorter and the depressive thoughts that invariably came with it (i.e. "negative auto-brooding") took a superficial tone and evaporated rapidly. I also noticed that my dreams, for the first couple of weeks at least, were less intense but much longer and wide-ranging. This was very surprising to me: it felt like I was catching up with dream-work somehow . I am now over 1 month into it and the 2/3 am awakening has become very variable and very brief. I wake up fully rested even if some nights, I have the feeling of not sleeping very smoothly. Gradually, I came to trust the effect, which probably reinforces it. Zero side-effects for me. Depending on one's metabolism, there will be some trial and error as to when to take it. I take it at around 9. The catch is to have the effect kick in at or just before the usual awakening time. This product does work and there is a simple, clear and logical explanation of why it does so that the placebo effect cannot account entirely for its efficacy. I reached the point where I am planning how to discontinue. I decided for 6 weeks of use. The hope, of course, is that the effect will continue, although, since the cortisol hypothesis has been confirmed in my case, chronic stress will likely take over eventually (until I change my life!). It will be interesting to see how long it takes and if there are any other changes. ### ⭐⭐⭐⭐⭐ Definitely Helpful *by M***U on March 21, 2016* Definitely has an effect... Did it immediately cure my night time waking problems (and can't fall back asleep) that I've had for about 11 years...No. I think its important to note that even though, for some, it might have allowed them to sleep immediately, its more realistic to think of this as part of a package to help you on the road to getting better. I've taken this for about 3 weeks now. The first week I started with one just before I went to bed. You might notice it makes you feel a bit strange at first, or when you increase dosage, but after a few days it goes away unless you are taking too much. I gradually increased it to 3 at one time before I went to bed and one when I'd wake up.....but I found it was affecting how I felt during the day. The key is that you'll have to play around with the dosages a bit, however if your issue is waking up at night between 12-2:30 then I would suggest you take one pill around 6pm and then another around 8-9 pm ...if you go to bed 10pm. Taking this did not consistently help me until I also started taking 1000mg of L-Tryptophan right at bedtime. Without the L-Tryptophan I found that I still woke up. though I still did feel better overall. The combination of the both of them has definitely helped and it seems that the longer I take a consistent dosage, my sleep gradually gets a bit better. I'm not cured by any means as it's only been 3 weeks, but I've noticed the last several days I'd wake up in the night but I would fall back asleep...I'd wake up again, fall asleep again...choppy but progress. Last night I woke up later and fell back asleep. It has been said that it can take a month to begin to have an effect, so I would suggest that you take it consistently for the first month without too much expectation. Note that this is for those with an over production of cortisol. If your sleep problems started during a stressful period, and has not corrected itself despite everything you've tried...then this is a good place to start. If you have any questions, feel free to leave them and I'll help you out as best I can. Like I mentioned, I've had this problem for around 11 years and I feel like I've finally have some hope of finally getting this fixed. Still a ways to go, but at least I see a light at the end of the tunnel. ## Frequently Bought Together - Seriphos - Phosphorylated Serine Adaptogen - Cortisol Supplement - Helps Cognitive Function, Gluten Free, Dairy Free, Soy Free - 100 Capsules - Life Extension Neuro-Mag Magnesium L-Threonate, Magnesium L-threonate, Memory Health, Quick Thinking, Cognitive Health Support, Vegetarian, Non-GMO, 90 Vegetarian Capsules - Pure Encapsulations Magnesium (Glycinate) - Supplement to Support Stress Relief, Sleep, Heart Health, Nerves, Muscles, and Metabolism* - with Magnesium Glycinate - 90 Capsules --- ## Why Shop on Desertcart? - 🛒 **Trusted by 1.3+ Million Shoppers** — Serving international shoppers since 2016 - 🌍 **Shop Globally** — Access 737+ million products across 21 categories - 💰 **No Hidden Fees** — All customs, duties, and taxes included in the price - 🔄 **15-Day Free Returns** — Hassle-free returns (30 days for PRO members) - 🔒 **Secure Payments** — Trusted payment options with buyer protection - ⭐ **TrustPilot Rated 4.5/5** — Based on 8,000+ happy customer reviews **Shop now:** [https://www.desertcart.co.uk/products/4115189-seriphos-phosphorylated-serine-adaptogen-cortisol-supplement-helps-cognitive-function-gluten](https://www.desertcart.co.uk/products/4115189-seriphos-phosphorylated-serine-adaptogen-cortisol-supplement-helps-cognitive-function-gluten) --- *Product available on Desertcart United Kingdom* *Store origin: GB* *Last updated: 2026-06-22*