--- product_id: 361203782 title: "S3 PYO Shampoo 16.9 oz (500 mL)" brand: "douxo" price: "£47.35" currency: GBP in_stock: true reviews_count: 5 category: "Douxo" url: https://www.desertcart.co.uk/products/361203782-s3-pyo-shampoo-16-9-oz-500-ml store_origin: GB region: Great Britain --- # ophytrium natural skin barrier reduces yeast in 7 days 500 mL soothing mousse S3 PYO Shampoo 16.9 oz (500 mL) **Brand:** douxo **Price:** £47.35 **Availability:** ✅ In Stock ## Summary > 🐾 Elevate your pet’s skin game with vet-trusted care that’s simply unstoppable! ## Quick Answers - **What is this?** S3 PYO Shampoo 16.9 oz (500 mL) by douxo - **How much does it cost?** £47.35 with free shipping - **Is it available?** Yes, in stock and ready to ship - **Where can I buy it?** [www.desertcart.co.uk](https://www.desertcart.co.uk/products/361203782-s3-pyo-shampoo-16-9-oz-500-ml) ## Best For - douxo enthusiasts ## Why This Product - Trusted douxo brand quality - Free international shipping included - Worldwide delivery with tracking - 15-day hassle-free returns ## Key Features - • **Perfect Pairing:** Maximize results by combining with DOUXO PYO Mousse for a complete skin health regimen. - • **Natural Barrier Boost:** Infused with purified ophytrium to soothe irritation and strengthen the skin’s protective ecosystem. - • **Rapid Yeast Reduction:** Clinically proven to lower yeast counts within just 7 days—because your pet deserves fast relief. - • **Clean & Gentle Formula:** Free from soaps, sulfates, parabens, dyes, and nanoparticles—pure care for sensitive skin. - • **Vet-Recommended Powerhouse:** The #1 non-prescription topical brand trusted by U.S. veterinarians for skin infections and inflammation. ## Overview Douxo S3 PYO Shampoo is a 500 mL hypoallergenic mousse formulated with antibacterial and antifungal ingredients, including natural ophytrium, to disinfect, moisturize, and support the skin barrier in dogs and cats. Clinically proven to reduce yeast counts in 7 days, it’s free from harsh chemicals and highly recommended by U.S. veterinarians for managing infections and inflammatory skin conditions. ## Description Formulated with antibacterial and antifungal ingredients to help soothe, clean and strengthen the skin barrier. Moisturizes and detangles the fur to leave the coat soft and shiny. DOUXO is the 1 non-prescription topical brand used and recommended by U.S. veterinarians for treatment of dogs and cats with infections/inflammatory dermatological diseases. Review: EXCELENTE PRODUCTO - EXCELENTE PRODUCTO, TENGO UNA BEAGLE CON SINDROME DE CUSHING + DERMATITIS ATOPICA, ASÍ QUE ES MUY COMÚN QUE RECAIGA EN SUS PROBLEMAS DE PIEL, CON ESTE SHAMPOO SUS PROBLEMAS HAN DISMINUIDO UN 80%, HE UTILIZADO MÁS DE 15 SHAMPOOS (SIN EXAGERAR) Y ESTE HA SIDO EL QUE MEJOR LE HA FUNCIONADO Y DISMINUIDO SUS BROTES EN LA PIEL, VALE LA PENA CADA PESO INVERTIDO EN ESTE SHAMPOO. Review: Excellent Shampoo ## Features - #1 non-prescription topical brand used and recommended by U.S. veterinarians for dogs and cats with infections/inflammatory dermatological disease - Proven to disinfect, hydrate and help support the skin's ecosystem and reduce yeast counts in 7 days - Contains ophytrium, a purified natural ingredient that helps support the skin’s physical barrier for supple hydrated skin and helps soothe irritated skin - Free from soaps, sulfates, parabens, dyes and nanoparticles - For best results use with the DOUXO PYO Mousse ## Technical Specifications | Specification | Value | |---------------|-------| | ASIN | B0949RKDYC | | Allergen Information | Hypoallergenic | | Best Sellers Rank | #13,620 in Pet Supplies ( See Top 100 in Pet Supplies ) #149 in Dog Shampoos | | Brand | DOUXO | | Brand Name | DOUXO | | Customer Reviews | 4.7 out of 5 stars 3,432 Reviews | | Included Components | Shampoo | | Item Form | Mousse | | Item Type Name | Shampoos & Conditioners | | Item Weight | 16.9 Ounces | | Item form | Mousse | | Liquid Volume | 500 Milliliters | | Manufacturer | Douxo S3 | | Material Type Free | soaps, sulfates, parabens, dyes, nanoparticles | | Material type free | soaps, sulfates, parabens, dyes, nanoparticles | | Product Benefits | Disinfectant, moisturizing and supporting the skin ecosystem, reducing yeast count in 7 days | | Product benefits | Disinfectant, moisturizing and supporting the skin ecosystem, reducing yeast count in 7 days | | Recommended Uses For Product | Irritated Skin,Moisturizing | | Recommended uses for product | Irritated Skin,Moisturizing | | Scent | Unscented | | Scent Name | Unscented | | Special Ingredients | ophytrium | | Target Species | Dogs and Cats | | UPC | 850002593433 | | Unit Count | 1 Count | ## Product Details - **Brand:** DOUXO - **Material type free:** soaps, sulfates, parabens, dyes, nanoparticles - **Product benefits:** Disinfectant, moisturizing and supporting the skin ecosystem, reducing yeast count in 7 days - **Recommended uses for product:** Irritated Skin,Moisturizing - **Scent:** Unscented ## Images ![S3 PYO Shampoo 16.9 oz (500 mL) - Image 1](https://m.media-amazon.com/images/I/61yhoJoV-IL.jpg) ## Available Options This product comes in different **Size** options. ## Questions & Answers **Q: What happened to the original formula that had these active ingredients: chlorhexadine 3%, climbazole .5%, phytosphingosine salicyloyl .05%??????** A: I talked to my Dog's Allergy Vet's office recently about this. They told me they reformulated this and took out some ingredients due to some Dog's having a reaction to it. Also, I don't like it and its nothing like the original formula. It doesn't suds up and I had to use more than double the amount the directions said on my 8 lb dog. **Q: I'm using the other brand of Douxo for my dog's skin allergies. How does this compare to the other Douxo?** A: This product is specifically designed to relieve bacterial or fungal skin infections. Specifically, it helps to soothe irritated skin. If your dog has skin allergies, this particular shampoo could be a good choice since it is the #1 non-prescription topical brand used and recommended by U.S. veterinarians. **Q: Why doesn't it say antifungal any more? it still says it in the description but no longer on the bottle? why?** A: Mine says antifungal anticeptic **Q: Who can i message that sells this product?** A: We do :) ## Customer Reviews ### ⭐⭐⭐⭐⭐ EXCELENTE PRODUCTO *by M***A on 12 January 2026* EXCELENTE PRODUCTO, TENGO UNA BEAGLE CON SINDROME DE CUSHING + DERMATITIS ATOPICA, ASÍ QUE ES MUY COMÚN QUE RECAIGA EN SUS PROBLEMAS DE PIEL, CON ESTE SHAMPOO SUS PROBLEMAS HAN DISMINUIDO UN 80%, HE UTILIZADO MÁS DE 15 SHAMPOOS (SIN EXAGERAR) Y ESTE HA SIDO EL QUE MEJOR LE HA FUNCIONADO Y DISMINUIDO SUS BROTES EN LA PIEL, VALE LA PENA CADA PESO INVERTIDO EN ESTE SHAMPOO. ### ⭐⭐⭐⭐⭐ Excellent Shampoo *by M***N on 4 August 2025* ### ⭐⭐⭐⭐⭐ HELP WITH MY BULLDOG SKIN 😍😍 *by S***O on 24 July 2024* ## Frequently Bought Together - Douxo S3 Pyo Shampoo, Contains 3% Chlorhexidine & 0.5% Ophytrium, Antiseptic & Hydrating, For Bacterial or Yeast Skin Infections, For Dogs and Cats, 16.9 fl. oz. (500mL) - Douxo S3 Pyo Mousse, Contains 3% Chlorhexidine & 0.5% Ophytrium, Antiseptic & Hydrating, for Bacterial or Yeast Skin Infections, for Dogs, 5.1 fl. oz. (150mL) - Douxo S3 Pyo Pads, Contains 3% Chlorhexidine & 0.5% Ophytrium, Antiseptic & Hydrating, For Bacterial or Yeast Skin Infections, For Dogs and Cats, 30 Pads --- ## Why Shop on Desertcart? - 🛒 **Trusted by 1.3+ Million Shoppers** — Serving international shoppers since 2016 - 🌍 **Shop Globally** — Access 737+ million products across 21 categories - 💰 **No Hidden Fees** — All customs, duties, and taxes included in the price - 🔄 **15-Day Free Returns** — Hassle-free returns (30 days for PRO members) - 🔒 **Secure Payments** — Trusted payment options with buyer protection - ⭐ **TrustPilot Rated 4.5/5** — Based on 8,000+ happy customer reviews **Shop now:** [https://www.desertcart.co.uk/products/361203782-s3-pyo-shampoo-16-9-oz-500-ml](https://www.desertcart.co.uk/products/361203782-s3-pyo-shampoo-16-9-oz-500-ml) --- *Product available on Desertcart Great Britain* *Store origin: GB* *Last updated: 2026-04-22*